Article
NF-κB Participates in the Stem Cell Phenotype of Ovarian Cancer Cells.
Archives of medical research - 1 May 2017
Gonzalez-Torres Carolina, Gaytan-Cervantes Javier, Vazquez-Santillan Karla, Mandujano-Tinoco Edna Ayerim, Ceballos-Cancino Gisela, Garcia-Venzor Alfredo, Zampedri Cecilia, Sanchez-Maldonado Paulina, Mojica-Espinosa Raul, Jimenez-Hernandez Luis Enrique, Maldonado Vilma
Abstract excerpt
BACKGROUND: NF-κB is a transcription factor involved in cancer stem cells maintenance of many tumors. Little is known about the specific stem-associated upstream regulators of this pathway in ovarian cancer. The Aim of the study was to analyze the role of the canonical and non-canonical NF-κB pathways in stem cells of ovarian cancer cell lines. METHODS: Stem cells were isolated using sorting cytometry. Western...
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