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Article

LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression

7 Sept 2017

Abstract excerpt

Long noncoding RNAs (lncRNAs) have important roles in various biological processes. Our previous work has revealed that dedifferentiation of retinal pigment epithelium (RPE) cells contributes to the pathology of age-related macular degeneration (AMD). Herein, we show roles of lncRNAs in RPE differentiation. We used microarray to identify lncRNA expression profiles in human induced pluripotent stem cells (hiPSCs)...

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PMID: 28880276
DOI: 10.1038/cddis.2017.382

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