Article
The effect of bovine BST2A1 on the release and cell-to-cell transmission of retroviruses.
Virology journal - 6 Sept 2017
Liang Zhibin, Zhang Yang, Song Jie, Zhang Hui, Zhang Suzhen, Li Yue, Tan Juan, Qiao Wentao
Abstract excerpt
BACKGROUND: Human BST2 (hBST2, also called Tetherin) is a host restriction factor that blocks the release of various enveloped viruses. BST2s from different mammals also possess antiviral activity. Bovine BST2s (bBST2s), bBST2A1 and bBST2A2, reduce production of cell-free bovine leukemia virus (BLV) and vesicular stomatitis virus (VSV). However, the effect of bBST2 on other retroviruses remains unstudied....
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