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Article

Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors.

Cancer letters - 10 Oct 2015

Lee Sun-Hwa, Hong Jun Hwa, Park Hwan Ki, Park Jun Seok, Kim Bo-Kyung, Lee Jung-Yi, Jeong Ji Yun, Yoon Ghil Suk, Inoue Masahiro, Choi Gyu-Seog, Lee In-Kyu

Abstract excerpt

Primary cultures of cancer cells are useful for developing personalized medicine. In this study, we characterized three lines of three-dimensional (3D) tumor spheroids established directly from tumor tissues of patients with colorectal cancers (CRCs). Each line mainly included EpCAM-positive cells and cells expressing putative cancer stem cell markers such as CD133, CD44, CD24, ALDH1, and LGR5. These...

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Identifiers

PMID: 26185002
DOI: 10.1016/j.canlet.2015.06.024

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KRAS
APC
MLH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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