Article
No Tissue Expression of KRAS or BRAF Mutations in 61 Adult Patients Treated for Esophageal Atresia in Early Childhood.
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie - 1 Oct 2018
Dang Kien Xuan, Ho Tho, Sistonen Saara, Koivusalo Antti, Pakarinen Mikko, Rintala Risto, Stenman Ulf-Hakan, Orpana Arto, Stenman Jakob
Abstract excerpt
BACKGROUND: Previous studies have reported an association among esophageal atresia (EA), Barrett's esophagus, and esophageal adenocarcinoma later in life. OBJECTIVE: The objective of the article is to evaluate KRAS and BRAF mutations as potential genetic markers for early detection of malignant transformation, we used an ultrasensitive technique to detect tissue expression of KRAS and BRAF mutations in endoscopic...
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