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Interspecies quorum sensing in co-infections can manipulate trypanosome transmission potential

4 Sept 2017

Abstract excerpt

Quorum sensing (QS) is commonly used in microbial communities and some unicellular parasites to coordinate group behaviours 1,2 . An example is Trypanosoma brucei, which causes human African trypanosomiasis, as well as the livestock disease, nagana. Trypanosomes are spread by tsetse flies, their transmission being enabled by cell-cycle arrested ‘stumpy forms’ that are generated in a density-dependent manner in...

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PMID: 28871083
DOI: 10.1038/s41564-017-0014-5

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