Article
Positively selected amino acid replacements within the RuBisCO enzyme of oak trees are associated with ecological adaptations.
PloS one - 1 Jan 2017
Hermida-Carrera Carmen, Fares Mario A, Fernández Ángel, Gil-Pelegrín Eustaquio, Kapralov Maxim V, Mir Arnau, Molins Arántzazu, Peguero-Pina José Javier, Rocha Jairo, Sancho-Knapik Domingo, Galmés Jeroni
Abstract excerpt
Phylogenetic analysis by maximum likelihood (PAML) has become the standard approach to study positive selection at the molecular level, but other methods may provide complementary ways to identify amino acid replacements associated with particular conditions. Here, we compare results of the decision tree (DT) model method with ones of PAML using the key photosynthetic enzyme RuBisCO as a model system to study...
Topics
- Adaptation, Physiological
- Amino Acid Substitution
- Chloroplasts
- Climate
- Decision Trees
- Evolution, Molecular
- Gene Expression
- Likelihood Functions
- Models, Molecular
- Mutation