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Article

Identification of novel RNA isoforms of LMNA.

Nucleus (Austin, Tex.) - 3 Sept 2017

DeBoy Emily, Puttaraju Madaiah, Jailwala Parthav, Kasoji Manjula, Cam Maggie, Misteli Tom

Abstract excerpt

The nuclear lamina is a proteinaceous meshwork situated underneath the inner nuclear membrane and is composed of nuclear lamin proteins, which are type-V intermediate filaments. The LMNA gene gives rise to lamin A and lamin C through alternative splicing. Mutations in LMNA cause multiple diseases known as laminopathies, including Hutchinson-Gilford Progeria Syndrome (HGPS), a premature aging disorder caused by a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28857661
DOI: 10.1080/19491034.2017.1348449
PMCID: PMC5703264

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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