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Article

Tumor location and patient age predict biological signatures of high-grade gliomas.

Neurosurgical review - 1 Apr 2018

Altieri Roberto, Zenga Francesco, Ducati Alessandro, Melcarne Antonio, Cofano Fabio, Mammi Marco, Di Perna Giuseppe, Savastano Riccardo, Garbossa Diego

Abstract excerpt

Prognostic factors for high-grade gliomas include patient age, IDH1 mutation, MGMT methylation, and Ki67 value. We assessed the predictive role of topographic location of gliomas for their biological signatures. Collecting all neuroradiological and histological data of patients with histologically proven HGG, we performed a retrospective monocentric study. A predictive value of frontal location for a lower Ki67...

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Share to Brain Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28856492
DOI: 10.1007/s10143-017-0899-8

Genes

IDH1
MGMT

Provenance

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