Article
Association between molecular alterations and tumor location and MRI characteristics in anaplastic gliomas.
Brain tumor pathology - 1 Apr 2015
Sonoda Yukihiko, Shibahara Ichiyoo, Kawaguchi Tomohiro, Saito Ryuta, Kanamori Masayuki, Watanabe Mika, Suzuki Hiroyoshi, Kumabe Toshihiro, Tominaga Teiji
Abstract excerpt
The aim of this study was to determine if molecular alterations are associated with tumor location and radiological characteristics in anaplastic gliomas. We performed a retrospective analysis of 122 anaplastic gliomas for molecular alterations (IDH1/2 mutations, TP53 mutations, and 1p19q co-deletion) to compare MRI features (location and image characteristics). We observed that IDH mutation is strongly...
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