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Article

Anatomical localization of isocitrate dehydrogenase 1 mutation: a voxel-based radiographic study of 146 low-grade gliomas.

European journal of neurology - 1 Feb 2015

Wang Y, Zhang T, Li S, Fan X, Ma J, Wang L, Jiang T

Abstract excerpt

BACKGROUND AND PURPOSE: A brain tumor's location is associated with the genetic profile of its tumor precursor cells. Mutations in isocitrate dehydrogenase 1 (IDH1) are an early event in tumor development and play a critical role in gliomagenesis. This study was conducted to specify the anatomical characteristics of IDH1 mutation in low-grade gliomas and to further explore the origin of gliomas with IDH1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25318355
DOI: 10.1111/ene.12578

Genes

IDH1

Provenance

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