Article
Chondrogenesis and osteogenesis are one continuous developmental and lineage defined biological process
24 Aug 2017
Abstract excerpt
Abstract Although chondrogenesis and osteogenesis are considered as two separate processes during endochondral bone formation after birth, recent studies have demonstrated the direct cell transformation from chondrocytes into bone cells in postnatal bone growth. Here we use cell lineage tracing and multiple in vivo approaches to study the role of Bmpr1a in endochondrogenesis. Our data showed profound changes in...