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Article

Clinical implications of neoepitope landscapes for adult and pediatric cancers.

Genome medicine - 31 Aug 2017

Feng Yang-Yang, Griffith Obi L, Griffith Malachi

Abstract excerpt

Many immunotherapies rely on the presence of neoepitopes derived from somatic mutations that lead to altered peptide sequences. Several studies have now analyzed the neoepitope landscape of different cancer subtypes, predominantly for adult samples, which tend to feature significantly higher mutational burden. However, a new report publishing the first comprehensive analysis of the pediatric neoepitope landscape...

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Identifiers

PMID: 28854952
DOI: 10.1186/s13073-017-0470-9
PMCID: PMC5577778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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