Article
The MC4R genotype is associated with postpartum weight reduction and glycemic changes among women with prior gestational diabetes: longitudinal analysis.
Scientific reports - 29 Aug 2017
de Carvalho Aline Martins, Shao Ping, Liu Huikun, Cheng Han-Ling, Zheng Yan, Leng Junhong, Li Weiqin, Huang Tao, Wang Tiange, Wang Leishen, Zhang Shuang, Hu Gang, Qi Lu
Abstract excerpt
The genetic variants near the Melanocortin-4 receptor gene (MC4R), a key protein regulating energy balance and adiposity, have been related to obesity and glucose metabolism. We aimed to assess whether the MC4R genotype affected longitudinal changes in body weight and glucose metabolism biomarkers among women with prior gestational diabetes mellitus (GDM). The MC4R genotype, postpartum weight reduction, and...
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