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Article

Familial risk for bipolar I disorder is associated with erythrocyte omega-3 polyunsaturated fatty acid deficits in youth with attention-deficit hyperactivity disorder.

Psychiatry research - 1 Jul 2022

McNamara Robert K, Chen Constance, Tallman Maxwell J, Schurdak Jennifer D, Patino L Rodrigo, Blom Thomas J, DelBello Melissa P

Abstract excerpt

Although attention-deficit/hyperactivity disorder (ADHD) and a family history of bipolar I disorder (BD) increase the risk for developing BD, associated pathoetiological mechanisms remain poorly understood. One candidate risk factor is a neurodevelopmental deficiency in omega-3 polyunsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). This study investigated erythrocyte...

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PMID: 35550258
DOI: 10.1016/j.psychres.2022.114587

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