Article
Transcriptional regulation and influence on replication of the human cytomegalovirus UL138 1.4 kb transcript.
Molecular medicine reports - 1 Oct 2017
Han Liying, Ma Yanping, Liu Zhongyang, Liu Chang, Lu Ying, Qi Ying, Huang Yujing, Sun Zhengrong, Ruan Qiang
Abstract excerpt
Human cytomegalovirus (HCMV) exists in a latent form in hematopoietic progenitors and undifferentiated cells of myeloid lineage. Protein UL138, encoded by the UL/b' region of the viral genome, serves an important role in the establishment and/or persistence of HCMV latency. However, little information about transcriptional regulation of the UL138 gene has been reported thus far. In the present study, the...
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