Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype.

PloS one - 1 Jan 2017

Berggren Olof, Hagberg Niklas, Alexsson Andrei, Weber Gert, Rönnblom Lars, Eloranta Maija-Leena

Abstract excerpt

BACKGROUND: Hyperactive B cells and a continuous interferon (IFN)-α production by plasmacytoid dendritic cells (pDCs) play a key role in systemic lupus erythematosus (SLE). We asked whether the interaction between B cells and pDCs stimulated with RNA-containing immune complexes affects peripheral B cell subsets. METHODS: B cells and pDCs were isolated from blood of healthy individuals and stimulated with immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen-Antibody Complex
Share to B-Lymphocyte Subsets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coculture Techniques

Share to Dendritic Cells

Share to Immunologic Memory

Share to Interleukin-10

Share to Interleukin-6

Share to Lupus Erythematosus, Systemic

Source

Open in PubMed Open full text

Identifiers

PMID: 28846748
DOI: 10.1371/journal.pone.0183946
PMCID: PMC5573130

Genes

CCL3
CCL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype.PMID 28846748Read ↗

Lupus Immune Complexes Drive Distinct Pro-Inflammatory Monocyte and Macrophage Populations Independent of Type I InterferonSemantic proximity Read ↗

Integrated analysis of competing endogenous RNA networks in peripheral blood mononuclear cells of systemic lupus erythematosusSemantic proximity Read ↗

Integrative transcriptomic analysis of SLE reveals IFN-driven cross-talk between immune cellsSemantic proximity Read ↗

microRNA downregulation in plasmacytoid dendritic cells in interferon-positive systemic lupus erythematosus and antiphospholipid syndromeSemantic proximity Read ↗

Plasmablast-like Phenotype Among Antigen-Experienced CXCR5-CD19low B Cells in Systemic Lupus Erythematosus.Semantic proximity Read ↗

MicroRNAs in the key events of systemic lupus erythematosus pathogenesis.Semantic proximity Read ↗

LncRNA NEAT1 promotes IL-6 secretion in monocyte-derived dendritic cells via sponging miR-365a-3p in systemic lupus erythematosusSemantic proximity Read ↗

Single-Cell Transcriptome Analysis Reveals Interaction between CCL19+ Inflammatory Keratinocytes and CCR7+ Dendritic Cells and B Cells in PemphigusSemantic proximity Read ↗

Dendritic cells' characteristics in patients with treated systemic lupus erythematosus.Semantic proximity Read ↗

Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses.Semantic proximity Read ↗

Lupus IgA1 autoantibodies synergize with IgG to enhance pDC responses to RNA-containing immune complexesSemantic proximity Read ↗

Type I interferon drives dysfunction of a distinct CD8+ HLA-DRB1+ T cell subset in systemic lupus erythematosusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.