Article
Validation of ALK/ROS1 Dual Break Apart FISH Probe probe in non-small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2017
Lim Sun Min, Chang Hyun, Cha Yoon Jin, Liang Shile, Tai Yan Chin, Li Gu, Pestova Ekaterina, Policht Frank, Perez Thomas, Soo Ross A, Park Won Young, Kim Hye Ryun, Shim Hyo Sup, Cho Byoung Chul
Abstract excerpt
BACKGROUND: ALK and ROS1 gene rearrangements are distinct molecular subsets of non-small-cell lung cancer (NSCLC), and they are strong predictive biomarkers of response to ALK/ROS1 inhibitors, such as crizotinib. Thus, it is clinically important to develop an effective screening strategy to detect patients who will benefit from such treatment. In this study, we aimed to validate analytical performance of Vysis...
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