Article
Programmed death-ligand 1 expression and T790M status in EGFR-mutant non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2017
Hata Akito, Katakami Nobuyuki, Nanjo Shigeki, Okuda Chiyuki, Kaji Reiko, Masago Katsuhiro, Fujita Shiro, Yoshida Hiroshi, Zama Kota, Imai Yukihiro, Hirata Yukio
Abstract excerpt
BACKGROUND: Differential biology and prognosis between T790M+ and T790M- populations imply immunological differences also. METHODS: We retrospectively analyzed programmed death-ligand 1 (PD-L1) expression and T790M status in rebiopsied samples of epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC). PD-L1 immunohistochemistry was performed using the SP142 antibody for tumour cell (TC)...
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