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Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs

24 Aug 2017

Abstract excerpt

Metabolic changes within the cell and its niche affect cell fate and are involved in many diseases and disorders including cancer and viral infections. Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma (KS). KSHV latently infected cells express only a subset of viral genes, mainly located within the latency-associated region, among them 12 microRNAs. Notably, these miRNAs...

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Cytomegalovirus and herpesvirus research
Extracellular vesicles in disease
Parvovirus B19 Infection Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28837697
DOI: 10.1371/journal.ppat.1006524

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