Getting the flu: 5 key facts about influenza virus evolution

Abstract excerpt

The year 1918 saw the most famous influenza pandemic—a worldwide epidemic that caused nearly 50 million deaths—when an H1N1 influenza A virus of partial avian origin infected over one-third of the world’s population. Although its exact origins are still under debate, World War I and trade routes are thought to have aided in the circulation of the virus worldwide [1]. Within the last century, there have been 4...

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