Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments.

Scientific reports - 23 Aug 2017

Talkenberger Katrin, Cavalcanti-Adam Elisabetta Ada, Voss-Böhme Anja, Deutsch Andreas

Abstract excerpt

During tissue invasion individual tumor cells exhibit two interconvertible migration modes, namely mesenchymal and amoeboid migration. The cellular microenvironment triggers the switch between both modes, thereby allowing adaptation to dynamic conditions. It is, however, unclear if this amoeboid-mesenchymal migration plasticity contributes to a more effective tumor invasion. We address this question with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Cell Movement
Share to Chemotaxis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computer Simulation

Share to Extracellular Matrix

Share to Neoplasm Invasiveness

Share to Neoplasms

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 28835679
DOI: 10.1038/s41598-017-09300-3
PMCID: PMC5569097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments.PMID 28835679Read ↗

A model of cell migration within the extracellular matrix based on a phenotypic switching mechanism.Semantic proximity Read ↗

Modeling the Transitions between Collective and Solitary Migration Phenotypes in Cancer MetastasisSemantic proximity Read ↗

The Anomalous Diffusion of a Tumor Invading with Different Surrounding TissuesSemantic proximity Read ↗

Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.Semantic proximity Read ↗

Phenotypic switching mechanisms determine the structure of cell migration into extracellular matrix under the 'go-or-grow' hypothesis.Semantic proximity Read ↗

Modeling, signaling and cytoskeleton dynamics: integrated modeling‐experimental frameworks in cell migrationSemantic proximity Read ↗

Bridging the Gap in Cancer Cell Behavior Against Matrix Stiffening: Insights from a Trizonal ModelSemantic proximity Read ↗

Integrating in vitro experiments with in silico approaches for Glioblastoma invasion: the role of cell-to-cell adhesion heterogeneitySemantic proximity Read ↗

Tumour heterogeneity promotes collective invasion and cancer metastatic disseminationSemantic proximity Read ↗

The three-way switch operation of Rac1/RhoA GTPase-based circuit controlling amoeboid-hybrid-mesenchymal transitionSemantic proximity Read ↗

Mathematical Models of Cancer Cell PlasticitySemantic proximity Read ↗

Modeling and predictions of biphasic mechanosensitive cell migration altered by cell-intrinsic properties and matrix confinement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.