Article
Genetic variation in adaptability and pleiotropy in budding yeast.
eLife - 17 Aug 2017
Jerison Elizabeth R, Kryazhimskiy Sergey, Mitchell James Kameron, Bloom Joshua S, Kruglyak Leonid, Desai Michael M
Abstract excerpt
Evolution can favor organisms that are more adaptable, provided that genetic variation in adaptability exists. Here, we quantify this variation among 230 offspring of a cross between diverged yeast strains. We measure the adaptability of each offspring genotype, defined as its average rate of adaptation in a specific environmental condition, and analyze the heritability, predictability, and genetic basis of this...
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