Article
Family history of cancer predicts endometrial cancer risk independently of Lynch Syndrome: Implications for genetic counselling.
Gynecologic oncology - 1 Nov 2017
Johnatty Sharon E, Tan Yen Y, Buchanan Daniel D, Bowman Michael, Walters Rhiannon J, Obermair Andreas, Quinn Michael A, Blomfield Penelope B, Brand Alison, Leung Yee, Oehler Martin K, Kirk Judy A, O'Mara Tracy A, Webb Penelope M, Spurdle Amanda B
Abstract excerpt
OBJECTIVE: To determine endometrial cancer (EC) risk according to family cancer history, including assessment by degree of relatedness, type of and age at cancer diagnosis of relatives. METHODS: Self-reported family cancer history was available for 1353 EC patients and 628 controls. Logistic regression was used to quantify the association between EC and cancer diagnosis in ≥1 first or second degree relative, and...
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