Article
Epidemiology of Clostridium difficile in infants in Oxfordshire, UK: Risk factors for colonization and carriage, and genetic overlap with regional C. difficile infection strains.
PloS one - 1 Jan 2017
Stoesser Nicole, Eyre David W, Quan T Phuong, Godwin Heather, Pill Gemma, Mbuvi Emily, Vaughan Alison, Griffiths David, Martin Jessica, Fawley Warren, Dingle Kate E, Oakley Sarah, Wanelik Kazimierz, Finney John M, Kachrimanidou Melina, Moore Catrin E, Gorbach Sherwood, Riley Thomas V, Crook Derrick W, Peto Tim E A, Wilcox Mark H, Walker A Sarah
Abstract excerpt
BACKGROUND: Approximately 30-40% of children <1 year of age are Clostridium difficile colonized, and may represent a reservoir for adult C. difficile infections (CDI). Risk factors for colonization with toxigenic versus non-toxigenic C. difficile strains and longitudinal acquisition dynamics in infants remain incompletely characterized. METHODS: Predominantly healthy infants (≤2 years) were recruited in...
Topics
- Carrier State
- Clostridioides difficile
- Clostridium Infections
- Cluster Analysis
- Cross Infection
- DNA, Bacterial
- Diarrhea
- Evolution, Molecular