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Article

A GDF15 3' UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p.

PloS one - 1 Jan 2017

Teng Ming-Sheng, Hsu Lung-An, Juan Shu-Hui, Lin Wen-Chi, Lee Ming-Cheng, Su Cheng-Wen, Wu Semon, Ko Yu-Lin

Abstract excerpt

Growth differentiation factor 15 (GDF15) is a strong predictor of cardiovascular events and mortality in individuals with or without cardiovascular diseases. Single nucleotide polymorphisms (SNPs) in microRNA (miRNA) target sites, also known as miRSNPs, are known to enhance or weaken miRNA-mRNA interactions and have been linked to diseases such as cardiovascular disease and cancer. In this study, we aimed to...

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PMID: 28806401
DOI: 10.1371/journal.pone.0183187
PMCID: PMC5555568

Genes

GDF15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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