Article
Impact of cell wall peptidoglycan O-acetylation on the pathogenesis of Staphylococcus aureus in septic arthritis.
International journal of medical microbiology : IJMM - 1 Oct 2017
Baranwal Gaurav, Mohammad Majd, Jarneborn Anders, Reddy Bommana Raghunath, Golla Archana, Chakravarty Sumana, Biswas Lalitha, Götz Friedrich, Shankarappa Sahadev, Jin Tao, Biswas Raja
Abstract excerpt
Staphylococcus aureus (S. aureus) is one of the most common pathogen causing septic arthritis. To colonize the joints and establish septic arthritis this bacterium needs to resist the host innate immune responses. Lysozyme secreted by neutrophils and macrophages is an important defense protein present in the joint synovial fluids. S. aureus is known to be resistant to lysozyme due to its peptidoglycan...
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