Why are pathogenic staphylococci so lysozyme resistant? The peptidoglycan <i>O</i>‐acetyltransferase OatA is the major determinant for lysozyme resistance of <i>Staphylococcus aureus</i>

Abstract excerpt

Staphylococcus species belong to one of the few bacterial genera that are completely lysozyme resistant, which greatly contributes to their persistence and success in colonizing the skin and mucosal areas of humans and animals. In an attempt to discover the cause of lysozyme resistance, we identified a gene, oatA, in Staphylococcus aureus. The corresponding oatA deletion mutant had an increased sensitivity to...

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