Article
Influence of Lys656Asn polymorphism of leptin receptor gene on leptin response secondary to two hypocaloric diets: a randomized clinical trial.
Annals of nutrition & metabolism - 1 Jan 2008
de Luis D A, Aller R, Izaola O, Sagrado M Gonzalez, Conde R
Abstract excerpt
BACKGROUND: Human obesity is characterized by high levels of leptin, and it has been suggested that obese patients may be leptin-resistant. OBJECTIVE: The aim of our study was to investigate the influence of Lys656Asn polymorphism in the LEPR gene on leptin response secondary to a low fat versus a low carbohydrate diet in obese patients. DESIGN: A population of 78 obesity patients was enrolled. Before and after 2...
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