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Article

Multiplexed molecular profiling of lung cancer using pleural effusion.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2014

Akamatsu Hiroaki, Koh Yasuhiro, Kenmotsu Hirotsugu, Naito Tateaki, Serizawa Masakuni, Kimura Madoka, Mori Keita, Imai Hisao, Ono Akira, Shukuya Takehito, Taira Tetsuhiko, Murakami Haruyasu, Ohde Yasuhisa, Endo Masahiro, Nakajima Takashi, Takahashi Toshiaki, Yamamoto Nobuyuki

Abstract excerpt

INTRODUCTION: Pleural effusion is frequently observed in patients with advanced lung cancer. Although effusion can be obtained less invasively and repeatedly, its use in multiplexed molecular profiling has not been fully investigated. METHODS: Between July 2011 and April 2013, pleural effusion samples were obtained from patients with lung cancer at Shizuoka Cancer Center. They were analyzed for EGFR, KRAS, BRAF,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24926551
DOI: 10.1097/JTO.0000000000000203

Genes

EGFR
ALK
KRAS
AKT1
BRAF
EML4
FGFR1
FGFR2
MET
NRAS
PTEN
RET
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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