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Article

Melanoma brain metastasis: the impact of stereotactic radiosurgery, BRAF mutational status, and targeted and/or immune-based therapies on treatment outcome.

Journal of neurosurgery - 1 Jul 2018

Kotecha Rupesh, Miller Jacob A, Venur Vyshak A, Mohammadi Alireza M, Chao Samuel T, Suh John H, Barnett Gene H, Murphy Erin S, Funchain Pauline, Yu Jennifer S, Vogelbaum Michael A, Angelov Lilyana, Ahluwalia Manmeet S

Abstract excerpt

OBJECTIVE The goal of this study was to investigate the impact of stereotactic radiosurgery (SRS), BRAF status, and targeted and immune-based therapies on the recurrence patterns and factors associated with overall survival (OS) among patients with melanoma brain metastasis (MBM). METHODS A total of 366 patients were treated for 1336 MBMs; a lesion-based analysis was performed on 793 SRS lesions. The BRAF status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 28799876
DOI: 10.3171/2017.1.JNS162797

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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