Article
Genetic association of telomere length with hepatocellular carcinoma risk: A Mendelian randomization analysis.
Cancer epidemiology - 1 Oct 2017
Cheng Yue, Yu Chengxiao, Huang Mingtao, Du Fangzhi, Song Ci, Ma Zijian, Zhai Xiangjun, Yang Yuan, Liu Jibin, Bei Jin-Xin, Jia Weihua, Jin Guangfu, Li Shengping, Zhou Weiping, Liu Jianjun, Dai Juncheng, Hu Zhibin
Abstract excerpt
BACKGROUND: Observational studies show an association between telomere length and Hepatocellular carcinoma (HCC) risk, but the relationship is controversial. Particularly, it remains unclear whether the association is due to confounding or biases inherent in conventional epidemiological studies. Here, we applied Mendelian randomization approach to evaluate whether telomere length is causally associated with HCC...
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