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Article

Comparative transcriptomes of adenocarcinomas and squamous cell carcinomas reveal molecular similarities that span classical anatomic boundaries.

PLoS genetics - 1 Aug 2017

Lin Eric W, Karakasheva Tatiana A, Lee Dong-Jin, Lee Ju-Seog, Long Qi, Bass Adam J, Wong Kwok K, Rustgi Anil K

Abstract excerpt

Advances in genomics in recent years have provided key insights into defining cancer subtypes "within-a-tissue"-that is, respecting traditional anatomically driven divisions of medicine. However, there remains a dearth of data regarding molecular profiles that are shared across tissues, an understanding of which could lead to the development of highly versatile, broadly applicable therapies. Using data acquired...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28787442
DOI: 10.1371/journal.pgen.1006938
PMCID: PMC5560753

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