Article
Flow cytometric sorting coupled with exon capture sequencing identifies somatic mutations in archival lymphoma tissues.
Laboratory investigation; a journal of technical methods and pathology - 1 Nov 2017
Jiang Nenggang, Chen Christopher, Gong Qiang, Shields Kristen, Li Yuping, Chen YuanYuan, Song Joo, McKeithan Timothy W, Chan Wing C
Abstract excerpt
The enormous number of archived formalin-fixed paraffin-embedded (FFPE) tissues available are a valuable resource of material for research. However, the use of such tissues poses many challenges, among which is the difficulty of isolating different cell populations within the tissue. In this study, we used tissue from two types of non-Hodgkin lymphoma as a model to demonstrate a method we have established and...
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