Prolonged Right Ventricular Ejection Delay in Brugada Syndrome Depends on the Type of SCN5A Variant　- Electromechanical Coupling Through Tissue Velocity Imaging as a Bridge Between Genotyping and Phenotyping.

doi:10.1253/circj.CJ-16-1279

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Prolonged Right Ventricular Ejection Delay in Brugada Syndrome Depends on the Type of SCN5A Variant　- Electromechanical Coupling Through Tissue Velocity Imaging as a Bridge Between Genotyping and Phenotyping.

Circulation journal : official journal of the Japanese Circulation Society - 25 Dec 2017

Van Malderen Sophie C H, Daneels Dorien, Kerkhove Dirk, Peeters Uschi, Theuns Dominic A M J, Droogmans Steven, Van Camp Guy, Weytjens Caroline, Biervliet Martine, Bonduelle Maryse, Van Dooren Sonia, Brugada Pedro

Abstract excerpt

BACKGROUND: Patients with Brugada syndrome (BrS) and a history of syncope or sustained ventricular arrhythmia have longer right ventricular ejection delays (RVEDs) than asymptomatic BrS patients. Different types ofSCN5Avariants leading to different reductions in sodium current (INa) may have different effects on conduction delay, and consequently on electromechanical coupling (i.e., RVED). Thus, we investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brugada Syndrome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Codon, Nonsense

Share to Cross-Sectional Studies

Share to Echocardiography

Share to Electrochemical Techniques

Share to Heart Conduction System

Share to Mutation, Missense

Share to NAV1.5 Voltage-Gated Sodium Channel

Source

Open in PubMed

Identifiers

PMID: 28781330
DOI: 10.1253/circj.CJ-16-1279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prolonged Right Ventricular Ejection Delay in Brugada Syndrome Depends on the Type of SCN5A Variant - Electromechanical Coupling Through Tissue Velocity Imaging as a Bridge Between Genotyping and Phenotyping.PMID 28781330Read ↗

Distinct Features of Probands With Early Repolarization and Brugada Syndromes Carrying SCN5A Pathogenic Variants.Semantic proximity Read ↗

Mechanisms of disease: current understanding and future challenges in Brugada syndrome.Semantic proximity Read ↗

Brugada Syndrome: From Molecular Mechanisms and Genetics to Risk Stratification.Semantic proximity Read ↗

A novel three base-pair deletion in domain two of the cardiac sodium channel causes Brugada syndrome.Semantic proximity Read ↗

Genetic and Molecular Mechanisms in Brugada Syndrome.Semantic proximity Read ↗

Brugada syndrome: clinical presentation and genotype-correlation with magnetic resonance imaging parameters.Semantic proximity Read ↗

Unravelling Novel SCN5A Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights.Semantic proximity Read ↗

Genotype-Phenotype Correlation of SCN5A Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome: A Japanese Multicenter Registry.Semantic proximity Read ↗

Association Between Deleterious SCN5A Variants and Ventricular Septal Defect in Young Patients With Brugada Syndrome.Semantic proximity Read ↗

Ventricular conduction is a marker for arrhythmic risk in SCN5A-E1784K overlap sodium channel disease.Semantic proximity Read ↗

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.Semantic proximity Read ↗

Clinical features of Brugada syndrome patients with SCN5A variantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.