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Article

Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis.

Inflammopharmacology - 1 Apr 2018

Grabarz Felipe, Aguiar Cristhiane Favero, Correa-Costa Matheus, Braga Tárcio Teodoro, Hyane Meire I, Andrade-Oliveira Vinícius, Landgraf Maristella Almeida, Câmara Niels Olsen Saraiva

Abstract excerpt

Pulmonary fibrosis is a result of an abnormal wound healing in lung tissue triggered by an excessive accumulation of extracellular matrix proteins, loss of tissue elasticity, and debit of ventilatory function. NKT cells are a major source of Th1 and Th2 cytokines and may be crucial in the polarization of M1/M2 macrophages in pulmonary fibrogenesis. Although there appears to be constant scientific progress in that...

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Identifiers

PMID: 28779430
DOI: 10.1007/s10787-017-0383-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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