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Article

From Ras to Rap and Back, a Journey of 35 Years.

Cold Spring Harbor perspectives in medicine - 1 Feb 2018

Bos Johannes L

Abstract excerpt

Our laboratory has studied Ras and Ras-like proteins since the discovery of the Ras oncogene 35 years ago. In this review, I will give an account of what we have done in these 35 years and indicate the main papers that have guided our research. Our efforts started with the early analysis of mutant Ras in human tumors followed by deciphering of the role of Ras in signal transduction pathways. In an attempt to...

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Identifiers

PMID: 28778969
DOI: 10.1101/cshperspect.a031468
PMCID: PMC5793741

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