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Article

Ganglioglioma with MAP2K1 Mutation and CDKN2A/B Homozygous Deletion: A Case Report.

British journal of hospital medicine (London, England : 2005) - 30 Oct 2024

Zhao Chi, Li Cheng, Ge Jing-Jing, Zhang Jun-Ping

Abstract excerpt

Aims/Background Gangliogliomas are grade 1 glioneuronal tumors occurring predominantly in the temporal lobe, as per the World Health Organization (WHO) classification. Gangliogliomas often harbor BRAF (v-Raf murine sarcoma viral oncogene homolog B1) p.V600E hotspot mutation or other alterations leading to activation of RAS/RAF/MAPK (rat sarcoma virus oncogene/rapidly accelerated fibrosarcoma/mitogen-activated...

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PMID: 39475028
DOI: 10.12968/hmed.2024.0379

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