Article
Cannabinoid receptor 2-63 RR variant is independently associated with severe necroinflammation in HIV/HCV coinfected patients.
PloS one - 1 Jan 2017
Sagnelli Caterina, Uberti-Foppa Caterina, Hasson Hamid, Bellini Giulia, Minichini Carmine, Salpietro Stefania, Messina Emanuela, Barbanotti Diletta, Merli Marco, Punzo Francesca, Coppola Nicola, Lazzarin Adriano, Sagnelli Evangelista, Rossi Francesca
Abstract excerpt
OBJECTIVE: This is the first study to analyze the impact of the rs35761398 variant of the CNR2 gene leading to the substitution of GLN (Q) of codon 63 of the cannabinoid receptor 2 (CB2) with ARG (R) on the clinical presentation of chronic hepatitis in HIV/HCV coinfected patients. METHODS: Enrolled in this study were 166 consecutive HIV/HCV coinfected patients, naïve for HCV treatment. A pathologist unaware of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.