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Article

Association between a polymorphism in cannabinoid receptor 2 and severe necroinflammation in patients with chronic hepatitis C.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Feb 2014

Coppola Nicola, Zampino Rosa, Bellini Giulia, Macera Margherita, Marrone Aldo, Pisaturo Mariantonietta, Boemio Adriana, Nobili Bruno, Pasquale Giuseppe, Maione Sabatino, Adinolfi Luigi Elio, Perrone Laura, Sagnelli Evangelista, Miraglia Del Giudice Emanuele, Rossi Francesca

Abstract excerpt

BACKGROUND & AIMS: The cannabinoid receptor 2 (CB2) has been implicated in liver disease. The single-nucleotide polymorphism rs35761398 in cannabinoid receptor 2 gene (CNR2), which encodes the CB2, substitutes glutamine (Q) 63 with arginine (R), and reduces the function of the gene product. We investigated the effects of CNR2 rs35761398 in patients with hepatitis C virus (HCV) infection. METHODS: We studied 169...

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Share to Asymptomatic Diseases
Share to Disease Progression
Share to Hepatitis C, Chronic
Share to Liver
Share to Logistic Models
Share to Mutation, Missense
Share to Receptor, Cannabinoid, CB2
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Source

Identifiers

PMID: 23707465
DOI: 10.1016/j.cgh.2013.05.008

Genes

CNR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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