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Characterization of a highly efficient antibiotic-degrading metallo-β-lactamase obtained from an uncultured member of a permafrost community.

Metallomics : integrated biometal science - 16 Aug 2017

Pedroso Marcelo Monteiro, Selleck Christopher, Enculescu Charmaine, Harmer Jeffrey R, Mitić Nataša, Craig Whitney R, Helweh Waleed, Hugenholtz Philip, Tyson Gene W, Tierney David L, Larrabee James A, Schenk Gerhard

Abstract excerpt

Antibiotic resistance is a major global health problem, one that threatens to derail the benefits garnered from arguably the greatest success of modern medicine, the discovery of antibiotics. Among the most potent agents contributing to antibiotic resistance are metallo-β-lactamases (MBLs). The discovery of MBL-like enzymes in microorganisms that are not in contact with the human population is of particular...

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PMID: 28749495
DOI: 10.1039/c7mt00195a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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