Article

The global β-lactam resistome revealed by comprehensive sequence analysis

2024-03-04

Abstract excerpt

Most antibiotic-resistance genes (ARGs) evolved in environmental microbes long before humanity’s antibiotic breakthrough, and widespread antibiotic use expedited the dissemination of ARGs among clinical pathogens. While widely discussed, the investigation of environmental ARG distributions lacks the scalability and taxonomic information necessary for a comprehensive analysis. Here, we present a global distribution...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d384fd9a-6119-53c1-a5de-bbc9dc4d26db
DOI: 10.1101/2024.03.01.583042

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The global β-lactam resistome revealed by comprehensive sequence analysisDOI 10.1101/2024.03.01.583042Read

Metagenomic insights into the distribution of antibiotic resistome between the gut-associated environments and the pristine environmentsSemantic proximity Read

Tackling Soil ARG‐Carrying Pathogens with Global‐Scale MetagenomicsSemantic proximity Read

Resistome Diversity in Escherichia coli Isolates of Global WastewatersSemantic proximity Read

Resistome prevalence and diversity in Escherichia coli isolates of global wastewatersSemantic proximity Read

Ecology, more than antibiotics consumption, is the major predictor for the global distribution of aminoglycoside-modifying enzymesSemantic proximity Read

Expanding the β‐Lactamase Family in the Human MicrobiomeSemantic proximity Read

Extensively acquired antimicrobial resistant bacteria restructure the individual microbial community in post-antibiotic conditionsSemantic proximity Read

Distinct Resistomes and Microbial Communities of Soils, Wastewater Treatment Plants and Households Suggest Development of Antibiotic Resistances Due to Distinct Environmental Conditions in Each EnvironmentSemantic proximity Read

Using Culture-Enriched Phenotypic Metagenomics for Targeted High-Throughput Monitoring of the Clinically Important Fraction of the β-Lactam ResistomeSemantic proximity Read

Metagenomic analysis after selective culture enrichment of wastewater demonstrates increased burden of antibiotic resistant genes in hospitals relative to the communitySemantic proximity Read

Community and Clinical Resistomes and Mobilomes: A CorrelationSemantic proximity Read

Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environmentSemantic proximity Read