Article
The crosstalk between efflux pump and resistance gene mutation in Helicobacter pylori.
Gut microbes - 1 Jan 2000
Gong Xiaoling, Wang Youhua, An Ying, Li Zhen, Liu Dongsheng, Yong Xie
Abstract excerpt
Efflux pumps play a crucial role in the development of antibiotic resistance. The aim of this study was to investigate the relationship between efflux pump gene expression and resistance gene mutations in Helicobacter pylori. Twenty-six clinical strains with varying resistance characteristics were selected for further experiment. Seven susceptible strains were induced to become resistant, and the expression of...
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