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Article

Associations between PPARG polymorphisms and the risk of essential hypertension.

PloS one - 1 Jan 2017

Cai Gaojun, Zhang Xinyong, Weng Weijin, Shi Ganwei, Xue Sheliang, Zhang Bifeng

Abstract excerpt

BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARG) plays an important role in the pathogenesis and maintenance of essential hypertension (EH). It has been suggested that polymorphisms of PPARG are associated with the risk of EH. However, findings to date remain controversial. To elucidate the associations between the PPARG Pro12Ala and C161T polymorphisms and EH risk, a meta-analysis was carried...

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Source

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Identifiers

PMID: 28727849
DOI: 10.1371/journal.pone.0181644
PMCID: PMC5519177

Genes

PPARG
VIP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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