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Article

Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines.

Scientific reports - 19 Jul 2017

Hernandez-Vargas Hector, Gruffat Henri, Cros Marie Pierre, Diederichs Audrey, Sirand Cécilia, Vargas-Ayala Romina C, Jay Antonin, Durand Geoffroy, Le Calvez-Kelm Florence, Herceg Zdenko, Manet Evelyne, Wild Christopher P, Tommasino Massimo, Accardi Rosita

Abstract excerpt

Epstein-Barr virus (EBV) was identified as the first human virus to be associated with a human malignancy, Burkitt's lymphoma (BL), a pediatric cancer endemic in sub-Saharan Africa. The exact mechanism of how EBV contributes to the process of lymphomagenesis is not fully understood. Recent studies have highlighted a genetic difference between endemic (EBV+) and sporadic (EBV-) BL, with the endemic variant showing...

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Identifiers

PMID: 28724958
DOI: 10.1038/s41598-017-05713-2
PMCID: PMC5517637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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