Article
Search for DQ2.5 and DQ8 alleles using a lower cost technique in patients with type 1 diabetes and celiac disease in a population of southern Brazil.
Archives of endocrinology and metabolism - 1 Dec 2017
Bastos Marília D, Kowalski Thayne W, Puñales Márcia, Tschiedel Balduíno, Mariath Luiza M, Pires Ana Luiza G, Faccini Lavínia S, Silveira Themis R
Abstract excerpt
OBJECTIVE: To evaluate the frequency of DQ2.5 and DQ8 alleles using the Tag-single-nucleotide polymorphism (Tag-SNP) technique in individuals with type 1 diabetes mellitus (T1DM) and celiac disease (CD) in southern Brazil. MATERIALS AND METHODS: In a prospective design, we performed the search for DQA1*0501 and DQB1*0201 alleles for DQ2.5 and DQB1*0302 for DQ8 through Real-Time Polymerase Chain Reaction (RT-PCR)...
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