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Article

Genomic signatures of pancreatic adenosquamous carcinoma (PASC).

The Journal of pathology - 1 Oct 2017

Fang Yuan, Su Zhe, Xie Jing, Xue Ruidong, Ma Qi, Li Yanmeng, Zhao Yifan, Song Zeshi, Lu Xiongxiong, Li Hongwei, Peng Chenghong, Bai Fan, Shen Baiyong

Abstract excerpt

In pancreatic cancer, pancreatic adenosquamous carcinoma (PASC) containing both ductal adenocarcinoma and squamous carcinoma in the same tumour represents ∼4% of the total incidence. To date, the genomic features of this mixed tumour are still unknown. We analysed the genomes of 17 PASCs and 34 pancreatic ductal adenocarcinomas (PDACs), and showed that PASC carried highly enriched TP53 mutations and 3p loss as...

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PMID: 28722109
DOI: 10.1002/path.4943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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