Article
Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2009
Brody Jonathan R, Costantino Christina L, Potoczek Magdalena, Cozzitorto Joseph, McCue Peter, Yeo Charles J, Hruban Ralph H, Witkiewicz Agnieszka K
Abstract excerpt
Adenosquamous carcinoma of the pancreas is one of the most aggressive forms of pancreatic cancer. Molecular characterizations of this rare tumor subtype are sparse. Understanding the common molecular and pathologic features of pancreatic adenosquamous carcinomas could provide critical information for identifying therapeutic targets. Herein, we analyzed the pathologic and molecular features of our series of eight...
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