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Article

The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer’s disease

15 Oct 2015

Abstract excerpt

Age-dependent cognitive decline is a major debilitating event affecting even individuals who are otherwise healthy. Understanding the molecular basis underlying these changes may increase the healthspan of the elderly population. It may also reveal insights into the pathogenesis of numerous neurodegenerative disorders characterized by cognitive deficits, as aging is the major risk factor for most of these...

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PMID: 28721257
DOI: 10.1038/npjamd.2015.8

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