Article
CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine.
Leukemia & lymphoma - 1 Apr 2018
Allan John N, Roboz Gail J, Askin Gulce, Ritchie Ellen, Scandura Joseph, Christos Paul, Hassane Duane C, Guzman Monica L
Abstract excerpt
We investigated CD25 expression in older (≥60 years) patients with new acute myelogenous leukemia treated with decitabine and plerixafor. Patients resistant to therapy or survival ≤1 year had significantly higher percentages of CD25pos myeloid blasts in baseline bone marrow. CD25pos patients had an increased odds of resistance compared to CD25neg patients (p = .015). In univariate analysis, we found CD25pos...
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